HMPV NOT A NEW PATHOGEN, CASES HAVE BEEN REPORTED WORLDWIDE

Human Metapneumovirus (HMPV) is a globally recognised respiratory virus that recently gained attention after its outbreak was reported in China. Here is an explainer on the HMPV:

What is HMPV?- HMPV is a viral pathogen that causes respiratory infections in people of all age groups. First discovered in 2001, it belongs to the Paramyxoviridae family and is closely related to Respiratory Syncytial Virus (RSV). HMPV spreads through respiratory droplets from coughing or sneezing, as well as by touching contaminated surfaces or coming into direct contact with infected individuals.

This virus is known to cause illnesses ranging from mild respiratory discomfort to severe complications, especially in vulnerable populations such as infants, older adults and individuals with weakened immune systems. It is prevalent globally and tends to peak during late winter and early spring in temperate regions, although it circulates year-round in some areas.

Transmission and Prevention: HMPV spreads in ways similar to other respiratory viruses such as RSV and influenza. Transmission occurs primarily through respiratory droplets from infected individuals or contact with contaminated surfaces. To prevent the spread of HMPV, practising good hand hygiene is essential, including frequent handwashing with soap and water.

Respiratory etiquette, such as covering the mouth and nose while sneezing or coughing and wearing a mask, can also limit the spread. Avoiding close contact with infected individuals and regularly disinfecting frequently touched surfaces are additional preventive measures.

How long does it last? Mild cases of human HMPV usually last a few days to a week. In severe cases, it will probably take longer to feel better. However, lingering symptoms, like a cough, may take longer to go away.

Diagnosis of HMPV: Diagnosing HMPV based solely on symptoms can be challenging, as it mimics other respiratory infections like RSV and influenza. Reverse Transcription Polymerase Chain Reaction (RT-PCR) is the gold standard diagnostic tool for detecting HMPV RNA, while antigen detection assays offer quicker results. In India, surveillance programmes like the ICMR and the Integrated Disease Surveillance Programme (IDSP) regularly test for respiratory viruses, including HMPV, as part of their efforts to monitor and control respiratory illnesses.

Treatment of HMPV: Currently, there is no specific antiviral medication or vaccine available for HMPV. Treatment is supportive and depends on the severity of the infection. For mild cases, rest, adequate hydration and over-the-counter medications to manage fever and nasal congestion are sufficient. In severe cases, particularly those involving pneumonia or bronchiolitis, oxygen therapy and hospitalisation may be required.

Patients experiencing significant respiratory distress may need mechanical ventilation. While research is going on to develop targeted therapies and vaccines, preventive measures and early medical intervention remain key to managing HMPV infections. — AP

The symptoms of HMPV vary depending on the individual's age, general health and immune response. Mild cases typically present with a runny nose, sore throat, cough and fever, resembling a common cold. Moderate symptoms may include persistent cough, wheezing and fatigue. In severe cases, especially in infants, older adults, and those with chronic illnesses, HMPV can lead to complications such as bronchitis, bronchiolitis or pneumonia. Severe Acute Respiratory Illness (SARI) requiring hospitalisation may also occur. These severe presentations are particularly concerning for high-risk groups.